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Association details:
Biomarker:
No biomarker
Cancer:
Childhood B Acute Lymphoblastic Leukemia
Drug:
bortezomib
(
Proteasome inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: A2 - Guideline
New
Source:
NCCN
Excerpt:
Pediatric Acute Lymphoblastic Leukemia: Other Recommended Regimens…Bortezomib-containing regimen: eg, bortezomib, vincristine, doxorubicin, pegaspargase, and prednisone or dexamethasone.
Secondary therapy:
doxorubicin hydrochloride + vincristine + prednisone + pegaspargase; doxorubicin hydrochloride + vincristine + dexamethasone + pegaspargase
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