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Association details:
| Biomarker: | No biomarker |
|---|---|
| Cancer: | B Acute Lymphoblastic Leukemia |
| Drug: | cytarabine (DNA synthesis inhibitor, DNA-directed DNAP inhibitor) + methotrexate (THF dehydrogenase inhibitor, Dihydrofolic acid reductase inhibitor) + idarubicin hydrochloride (Topoisomerase II inhibitor, DNA cross linking agent) |
| Direction: | Sensitive |
Evidence:
Source:
Excerpt:
REGIMENS FOR RELAPSED OR REFRACTORY Ph-NEGATIVE B-ALL…Other Recommended Regimens...Cytarabine-containing regimens: eg, high-dose cytarabine, idarubicin, IT methotrexate