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    Association details:
    Biomarker:No biomarker
    Cancer:B Acute Lymphoblastic Leukemia
    Drug:cytarabine (DNA synthesis inhibitor, DNA-directed DNAP inhibitor) +
    etoposide IV (Topoisomerase II inhibitor) +
    mitoxantrone (Topoisomerase II inhibitor)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: A2 - Guideline
    Source:
    NCCN
    Published date:
    04/04/2022
    Excerpt:
    REGIMENS FOR RELAPSED OR REFRACTORY Ph-NEGATIVE T-ALL...Other Recommended Regimens...Mitoxantrone, etoposide, and cytarabine