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    Association details:
    Biomarker:NKX2-1 expression
    Cancer:Merkel Cell Carcinoma
    Drug:Bavencio (avelumab) (PD-L1 inhibitor)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: C4 – Case Studies
    Source:
    J Dermatol
    Title:

    Single administration of avelumab induced a complete response in thyroid transcription factor 1-positive combined Merkel cell carcinoma

    Published date:
    08/13/2020
    Excerpt:
    ...this case study presents a rare case of TTF-1-positive combined MCC showing complete response after a single administration of avelumab.
    DOI:
    https://doi.org/10.1111/1346-8138.15543