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Association details:
| Biomarker: | NICD expression |
|---|---|
| Cancer: | Colorectal Cancer |
| Drug: | Avastin (bevacizumab) (VEGF-A inhibitor) |
| Direction: | Resistant |
Evidence:
Source:
Title:
452P - Predicting response to bevacizumab in colorectal cancer by integrating radiomics to clinical and genomic features
Published date:
09/13/2021
Excerpt:
In our retrospective analysis, Notch signalling pathway was associated with resistance to anti-vascular endothelial growth factor (VEGF) therapy in patients with metastatic colorectal cancer (mCRC)....NICD and JAG1 expression was associated with response to bevacizumab (p<0.05).