^
Association details:
| Biomarker: | NGFR overexpression |
|---|---|
| Cancer: | Squamous Cell Skin Cancer |
| Drug: | 5-fluorouracil (Thymidylate synthase inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
051 CD271 activation reduces SCC spheroid aggressiveness, modulates keratinocyte differentiation and favors response to therapy
Published date:
04/19/2021
Excerpt:
Upon CD271 overexpression, photodynamic therapy or chemotherapy (5FU or cisplatin) reduce cSCC spheroid size and viability to a higher degree as compared to the effect in mock spheroids.
DOI:
10.1016/j.jid.2021.02.068
