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Association details:
Evidence:
Evidence Level:
Resistant: C3 – Early Trials
Title:

Overexpression of NIMA related kinase 2 in multiple myeloma and its relevance with disease features and prognosis to bortezomib treatment

Published date:
09/10/2022
Excerpt:
Additionally, elevated NEK2 expression was correlated with declined objective response rate (ORR) (χ2 = 4.808, p = 0.028), but not with complete response (CR) (χ2 = 2.341, p = 0.126)...NEK2 overexpression links with occurrence of bone lesion, t (4; 14), and poor prognosis to bortezomib treatment in MM patients.
DOI:
10.1111/jcpt.13723