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Association details:
Biomarker:
MYD88 overexpression
Cancer:
Squamous Cell Carcinoma of Head and Neck
Drug:
Erbitux (cetuximab)
(
EGFR inhibitor
)
Direction:
Resistant
Evidence:
Evidence Level:
Resistant: D – Preclinical
Source:
Am J Cancer Res
Title:
TLR4 activation leads to anti-EGFR therapy resistance in head and neck squamous cell carcinoma
Published date:
03/21/2020
Excerpt:
MyD88 overexpressed SCC4 cells grew faster and were almost resistant to cetuximab therapy.
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