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Association details:
Biomarker:MSI-H/dMMR
Cancer:Endometrial Cancer
Drug:Imfinzi (durvalumab) (PD-L1 inhibitor)
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: A1 - Approval
Title:

Imfinzi plus chemotherapy approved in the US for mismatch repair deficient advanced or recurrent endometrial cancer

Published date:
06/17/2024
Excerpt:
AstraZeneca’s Imfinzi (durvalumab) in combination with carboplatin and paclitaxel followed by Imfinzi monotherapy has been approved in the US as treatment for adult patients with primary advanced or recurrent endometrial cancer that is mismatch repair deficient (dMMR).
Secondary therapy:
carboplatin + paclitaxel