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    Association details:
    Biomarker:miR-324-5p overexpression
    Cancer:Lung Cancer
    Drug:cisplatin (DNA synthesis inhibitor)
    Direction:Resistant
    Evidence:
    Evidence Level:
    Resistant: C3 – Early Trials
    Source:
    J Biochem
    Title:

    miR-324-5p upregulation potentiates resistance to cisplatin by targeting FBXO11 signalling in non-small cell lung cancer cells

    Published date:
    09/16/2019
    Excerpt:
    Herein, we report that miR-324-5p expression was significantly increased in cisplatin (CDDP)-resistant LCa tissues and cells, and this upregulation predicted a poor post-chemotherapy prognosis in LCa patients.
    DOI:
    10.1093/jb/mvz066