MicroRNA-211 modulates the DUSP6-ERK5 signaling axis to promote BRAF V600E-driven melanoma growth in vivo and BRAF/MEK inhibitor resistance
Published date:
09/01/2020
Excerpt:
We therefore examined whether miR-211 similarly modulated melanoma resistance to the BRAF inhibitor vemurafenib and the MEK inhibitor cobimetinib. Consistent with this model, miR-211 expression increased melanoma cell resistance to both inhibitors…