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Association details:
| Biomarker: | miR-206 overexpression |
|---|---|
| Cancer: | Ovarian Cancer |
| Drug: | cisplatin (DNA synthesis inhibitor) |
| Direction: | Resistant |
Evidence:
Source:
Title:
miR-206 as a prognostic and sensitivity biomarker for platinum chemotherapy in epithelial ovarian cancer
Published date:
11/03/2020
Excerpt:
In vivo murine xenograft models showed that miR-206 profoundly promoted the chemoresistance of EOC to cisplatin treatment...The qRT-PCR results showed significantly higher miR-206 expression levels in C13 and A2780CP cells than in their cisplatin-sensitive counterparts.
DOI:
https://doi.org/10.1186/s12935-020-01623-y