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Association details:
| Biomarker: | miR-199a overexpression |
|---|---|
| Cancer: | Chronic Myeloid Leukemia |
| Drug Class: | Tyrosine kinase inhibitor |
| Direction: | Sensitive |
Evidence:
Source:
Title:
MIR-199A EXPRESSION PROFILES IN CHRONIC MYELOID LEUKEMIA: A PRELIMINARY STUDY
Published date:
05/12/2022
Excerpt:
This study was conducted in 12 CML patients treated with TKI therapy….MiR-199a is highly expressed in CML patients mainly with a deeper molecular response (Ratio=33.36 vs 5.94 for DMR and MMR respectively)….Despite the limit of our study, it underscores the importance of MiR-199a expression, as potential marker of optimal molecular evolution in patients under TKI therapy.
