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Association details:
| Biomarker: | miR-186 overexpression |
|---|---|
| Cancer: | Breast Cancer |
| Drug: | paclitaxel (Tubulin inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Resistance of breast cancer cells to paclitaxel is associated with low expressions of miRNA-186 and miRNA-7
Published date:
09/01/2023
Excerpt:
miR-186 and miR-7 expression in BC tissues was higher in patients with better outcomes of PTX-based neoadjuvant therapy....In conclusion, presented results showed that miR-185 and miR-7 expressions are higher in PTX-sensitive BC cells than in resistant cells. It was demonstrated for the first time that the overexpression of these molecules in BC tissues is associated with sensitivity to PTX...
DOI:
http://dx.doi.org/10.20517/cdr.2023.19