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Association details:
| Biomarker: | miR-155 overexpression |
|---|---|
| Cancer: | Oral Cancer |
| Drug: | cisplatin (DNA synthesis inhibitor) |
| Direction: | Resistant |
Evidence:
Source:
Title:
MiR-155 targeting FoxO3a regulates oral cancer cell proliferation, apoptosis, and DDP resistance through targeting FoxO3a
Published date:
12/30/2019
Excerpt:
The expression of miR-155 was significantly higher, while the expression of Foxo3a mRNA and protein was obviously lower in KB/DDP cells than that in KB cells....Increased expression of miR-155 and decreased expression of Foxo3a were associated with DDP resistance in oral cancer cells.
DOI:
10.3233/CBM-190555
