^
Association details:
| Biomarker: | miR-143-3p overexpression |
|---|---|
| Cancer: | Colorectal Cancer |
| Drug: | Avastin (bevacizumab) (VEGF-A inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
miR-7, miR-10a and miR-143 Expression May Predict Response to Bevacizumab Plus Chemotherapy in Patients with Metastatic Colorectal Cancer
Published date:
09/29/2021
Excerpt:
...expression of 26 miRNAs could be associated with the effectiveness of bevacizumab plus chemotherapy...The overexpression of miR-143-3p, however, was associated with a better prognosis and significantly better PFS (HR=0.57; 95% CI: 0.33– 0.96; p=0.033).
Secondary therapy:
Chemotherapy
DOI:
https://doi.org/10.2147/PGPM.S313594