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Association details:
| Biomarker: | miR‑106-a expression |
|---|---|
| Cancer: | Gastric Cancer |
| Drug: | AiTan (rivoceranib) (VEGFR-2 inhibitor) |
| Direction: | Resistant |
Evidence:
Source:
Title:
MicroRNA-106a-3p Induces Apatinib Resistance and Activates Janus-Activated Kinase 2 (JAK2)/Signal Transducer and Activator of Transcription 3 (STAT3) by Targeting the SOCS System in Gastric Cancer
Published date:
12/29/2019
Excerpt:
The results showed that the expression of miR-106a-3p was increased in apatinib‑resistant gastric cancer, while miR-106a-3p inhibitor reduced the drug-resistance of SGC-7901-AP cells to apatinib.
DOI:
10.12659/MSM.919610