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    Association details:
    Biomarker:MET overexpression
    Cancer:Non Small Cell Lung Cancer
    Drug:MG132 (Proteasome inhibitor)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: D – Preclinical
    Source:
    Oncol Res
    Title:

    Proteasome inhibitors diminish c-Met expression and induce cell death in non-small cell lung cancer cells

    Published date:
    06/24/2020
    Excerpt:
    Furthermore, MG-132 induced cell death in all fourcell types. Among all four cell lines, H441 cells expressed higher levels of c-Met andappeared to be the most susceptible to MG-132.
    DOI:
    10.3727/096504020X15929939001042