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Association details:
Biomarker:
MET overexpression + KDR overexpression
Cancer:
Glioblastoma
Drug:
Avastin (bevacizumab)
(
VEGF-A inhibitor
)
Direction:
Resistant
Evidence:
Evidence Level:
Resistant: C3 – Early Trials
Source:
Sci Rep
Title:
The role of c-Met and VEGFR2 in glioblastoma resistance to bevacizumab
Published date:
03/16/2021
Excerpt:
Concomitant c-Met/VEGFR2 overexpression was associated with worse overall survival (13 months) compared with concomitant c-Met/VEGFR2 negative expression (19 months; p = 0.025)
DOI:
10.1038/s41598-021-85385-1
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