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Association details:
Biomarker:
MET exon 14 mutation
Cancer:
Non Small Cell Lung Cancer
Drug:
CKD-702
(
c-MET inhibitor
,
EGFR antagonist
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
Source:
ESMO 2022
Title:
998P - A phase I study of CKD-702, an EGFR-cMET bispecific antibody, in advanced or metastatic non-small cell lung cancer (NSCLC)
Published date:
09/05/2022
Excerpt:
CKD-702 has a manageable safety profile related to EGFR and cMet inhibition, and showed preliminary response in patients with MET ex14 skipping.
Trial ID:
NCT04667975
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