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Association details:
| Biomarker: | MEF2D-CSF1R fusion |
|---|---|
| Cancer: | Chronic Myeloid Leukemia |
| Drug: | imatinib (Bcr-abl inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
RNA-seq identifies clinically relevant fusion genes in leukemia including a novel MEF2D/CSF1R fusion responsive to imatinib
Excerpt:
This revealed that imatinib impaired cell growth of the leukemic cells carrying MEF2D/CSF1R to a similar degree as that of leukemic cells from a CML carrying BCR/ABL1.
DOI:
10.1038/leu.2013.324