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Association details:
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
Title:

Phase 1 safety, pharmacokinetic and pharmacodynamic study of fadraciclib (CYC065), a cyclin dependent kinase inhibitor, in patients with advanced cancers

Published date:
10/26/2020
Excerpt:
Cyclacel Pharmaceuticals...announced clinical data demonstrating safety, anti-tumor activity and good oral bioavailability of Cyclacel's CDK2/9 inhibitor fadraciclib...A patient with MCL1 amplified endometrial cancer achieved partial response (PR) with 92% target tumor shrinkage on singe agent fadraciclib.
Trial ID: