^
Association details:
Biomarker:MCAM expression
Cancer:Solid Tumor
Drug:AMT-253 (CAR-T immunotherapy)
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Source:
Title:

A Cell Surface-Binding Antibody Atlas Nominates a MUC18-Directed Antibody-Drug Conjugate for Targeting Melanoma

Published date:
11/15/2023
Excerpt:
AMT-253 was also efficacious in a wide range of MUC18-expressing solid tumors.
DOI:
10.1158/0008-5472.CAN-23-1356