^
    Back
    Association details:
    Biomarker:MALAT1 underexpression
    Cancer:Non Small Cell Lung Cancer
    Drug:gefitinib (EGFR inhibitor)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: D – Preclinical
    New
    Source:
    Oncol Rep
    Title:

    Microarray expression profile of long non-coding RNAs in EGFR-TKIs resistance of human non-small cell lung cancer

    Excerpt:
    Overexpression of H19 and BC200 were observed in gefitinib-resistant lung cancer cell lines (PC9/R, A549, H1299 and H1975). However, in the gefitinib-sensitive cell line (PC9), MALAT1 and HOTAIR were downregulated (Fig. 5B).
    DOI:
    10.3892/or.2014.3643