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    Association details:
    Biomarker:MALAT1 overexpression
    Cancer:HER2 Positive Breast Cancer
    Drug:Herceptin (trastuzumab) (HER2 inhibitor)
    Direction:Resistant
    Evidence:
    Evidence Level:
    Resistant: D – Preclinical
    Source:
    Cancers (Basel)
    Title:

    Expression of MALAT1 Promotes Trastuzumab Resistance in HER2 Overexpressing Breast Cancers

    Published date:
    07/16/2020
    Excerpt:
    The highest level of MALAT1 was observed in metastatic triple-negative breast cancer and trastuzumab-resistant HER2 (human epidermal growth factor receptor 2) overexpressing (HER2+) cells.
    DOI:
    10.3390/cancers12071918