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    Association details:
    Biomarker:MALAT1 overexpression
    Cancer:Colorectal Cancer
    Drug:oxaliplatin (DNA synthesis inhibitor, DNA cross linking agent)
    Direction:Resistant
    Evidence:
    Evidence Level:
    Resistant: D – Preclinical
    New
    Source:
    Cancer Cell Int
    Title:

    Long non-coding RNA MALAT1 regulates oxaliplatin-resistance via miR-324-3p/ADAM17 axis in colorectal cancer cells

    Excerpt:
    Significant up regulation of MALAT1 and ADAM17, and decrease of miR-324-3p were observed in Ox-resistant CRC tissues and cells.
    DOI:
    10.1186/s12935-020-01549-5