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    Association details:
    Biomarker:MACC1-AS1 overexpression
    Cancer:Esophageal Squamous Cell Carcinoma
    Drug:cisplatin (DNA synthesis inhibitor)
    Direction:Resistant
    Evidence:
    Evidence Level:
    Resistant: D – Preclinical
    New
    Source:
    Mol Ther Nucleic Acids
    Title:

    Long non-coding RNAs MACC1-AS1 and FOXD2-AS1 mediate NSD2-induced cisplatin resistance in esophageal squamous cell carcinoma

    Excerpt:
    Here we examined the expression of NSDs in cisplatin-resistant and parental ESCC cells...Moreover, MACC1-AS1 overexpression promoted ESCC cell proliferation and cisplatin resistance.
    Secondary therapy:
    ; letrozole; fulvestrant
    DOI:
    10.1016/j.omtn.2020.12.007