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Association details:
Biomarker:LZTS1 overexpression
Cancer:Breast Cancer
Drug:paclitaxel (Tubulin inhibitor)
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Title:

Increased LZTS1 expression is associated with a good response to paclitaxel-based chemotherapy in breast cancer

Published date:
04/26/2022
Excerpt:
Overexpression of LZTS1 could sensitize human breast carcinoma xenografts to paclitaxel. In addition, tumor with high LZTS1 expression was more sensitive to chemotherapy with paclitaxel in breast cancer….
DOI:
https://doi.org/10.1016/j.prp.2022.153915