^
Association details:
| Biomarker: | LY9 expression |
|---|---|
| Cancer: | Chronic Lymphocytic Leukemia |
| Drug Class: | T-lymphocyte cell therapy |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Abstract 3250: CD229-targeted CAR T cell therapy for the treatment of B cell lymphoma
Published date:
08/15/2020
Excerpt:
...primary material from patients with B cell lymphoma revealed CD229 surface expression in 16/16 cases of B cell chronic lymphoblastic leukemia (B-CLL)...In addition to robust killing of B cell lymphoma cell lines, CD229 CAR T cells were also able to effectively kill primary cells from 4/4 mantle cell lymphoma patients and 3/3 B-CLL patients.
DOI:
10.1158/1538-7445.AM2020-3250
