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Association details:
Biomarker:LRP1B mutation
Cancer:Solid Tumor
Drug Class:Immunotherapy
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
Title:

The potential biomarkers of checkpoint inhibitor immunotherapy in solid malignancies.

Published date:
05/25/2020
Excerpt:
Eighty-one pts received IO who had NGS sent prior to treatment....Most common gene mutations in CR group were ROS1 (52.6%), LRP1B (52.6%), GRIN2A (47.4%), and EPHA7 (42.1%) in 19 patients.
DOI:
10.1200/JCO.2020.38.15_suppl.e15226