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Association details:
| Biomarker: | lncRNA DILA1 overexpression |
|---|---|
| Cancer: | Breast Cancer |
| Drug: | tamoxifen (Estrogen receptor antagonist) |
| Direction: | Resistant |
Evidence:
Source:
Title:
LncRNA DILA1 inhibits Cyclin D1 degradation and contributes to tamoxifen resistance in breast cancer
Published date:
11/02/2020
Excerpt:
High expression of DILA1 is associated with overexpressed Cyclin D1 protein and poor prognosis in breast cancer patients who received tamoxifen treatment….this Cyclin D1-interacting lncD1-8 that is upregulated and responsible for tamoxifen resistance is named as Cyclin D1-Interacting Long noncoding RNA 1 (DILA1).
DOI:
10.1038/s41467-020-19349-w
