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Association details:
| Biomarker: | LIFR D578N |
|---|---|
| Cancer: | Colorectal Cancer |
| Drug: | Erbitux (cetuximab) (EGFR inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Feasibility of proposed single-nucleotide polymorphisms as predictive markers for targeted regimens in metastatic colorectal cancer
Excerpt:
For the cetuximab regimens, patients homozygous for the wild-type alleles (GG) of LIFR rs3729740 exhibited greater ORR and DCR…
DOI:
10.1038/bjc.2013.163
