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Association details:
| Biomarker: | LCN2 overexpression |
|---|---|
| Cancer: | Colorectal Cancer |
| Drug: | Erbitux (cetuximab) (EGFR inhibitor) |
| Direction: | Resistant |
Evidence:
Source:
Title:
/ 29 - The high expression levels of HK1 (Hexokinase 1) results in resistance to cetuximab in colorectal cancer
Published date:
05/15/2020
Excerpt:
These finding highlights that this acquired resistance mechanism was observed in CRC, demonstrating the HK1 and LCN2 are novel biomarkers for cetuximab resistance.