^
Association details:
| Biomarker: | LATS1 mutation |
|---|---|
| Cancer: | Mesothelioma |
| Drug: | Visudyne (verteporfin) (Reactive oxygen species stimulant, Photosensitizer) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
FBXL20 promotes breast cancer malignancy by inhibiting apoptosis through degradation of PUMA and BAX
Published date:
09/26/2021
Excerpt:
...RASSF7 amplifcation and NF2 or LATS1/2 mutations were present in 50% of tumours and were accompanied by micromolar responses to the YAP1 inhibitor Verteporfn.
DOI:
https://doi.org/10.1016/j.jbc.2021.101253
