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    Association details:
    Biomarker:LAMC2 overexpression
    Cancer:Lung Cancer
    Drug:gefitinib (EGFR inhibitor)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: D – Preclinical
    Source:
    Cancer Gene Ther
    Title:

    LAMC2 promotes EGFR cell membrane localization and acts as a novel biomarker for tyrosine kinase inhibitors (TKIs) sensitivity in lung cancer

    Published date:
    08/04/2023
    Excerpt:
    ...our study showed that high LAMC2 expression is positively associated with response to gefitinib (EGFR tyrosine kinase inhibitor) treatment.
    DOI:
    https://doi.org/10.1038/s41417-023-00654-7