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Association details:
Biomarker:
KRAS K117
Cancer:
Colorectal Cancer
Drug:
Vectibix (panitumumab)
(
EGFR inhibitor
)
Direction:
Resistant
Evidence:
Evidence Level:
Resistant: A1 - Approval
New
Source:
FDA
Excerpt:
Vectibix is not indicated for the treatment of patients with colorectal cancer that harbor somatic RAS mutations in exon 2 (codons 12 and 13), exon 3 (codons 59 and 61), and exon 4 (codons 117 and 146) of either KRAS or NRAS…
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