^
Association details:
| Biomarker: | KRAS G13D |
|---|---|
| Cancer: | Colorectal Cancer |
| Drug: | MEN1611 (PI3K inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
The Selective Class I PI3K Inhibitor CH5132799 Targets Human Cancers Harboring Oncogenic PIK3CA Mutations
Excerpt:
...colorectal cancer HCT116, harboring both PIK3CA and KRAS mutations, showed strong tumor growth inhibition by CH5132799, consistent with our in vitro observations.
DOI:
10.1158/1078-0432.CCR-10-2882
