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Association details:
Evidence:
Evidence Level:
Sensitive: C4 – Case Studies
Title:

Complete response to nivolumab in Kirsten rat sarcoma virus oncogene KRAS-G12C mutant metastatic lung adenocarcinoma: a case report

Published date:
11/03/2022
Excerpt:
We report the case of a 58-year-old female Caucasian...who presented with cough and chest pain and was subsequently diagnosed with metastatic pulmonary adenocarcinoma....The tumor was positive for Kirsten rat sarcoma virus oncogene KRAS-G12C mutation and had high programmed death-1 ligand expression….She was then commenced on immunotherapy with nivolumab, with complete response for a total of 6 years. She does not report any adverse events. Currently, she shows no evidence of recurrence of non-small cell lung carcinoma.
DOI:
10.1186/s13256-022-03593-3