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Association details:
| Biomarker: | KMT2A rearrangement |
|---|---|
| Cancer: | Acute Lymphocytic Leukemia |
| Drug: | azacitidine (DNA methylation inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Azacitidine successfully maintained the second remission in an infant with KMT2A-rearranged acute lymphoblastic leukemia who relapsed after unrelated cord blood transplantation
Excerpt:
We report an infant MLL‐r ALL case with post‐HSCT relapse. After achieving a second remission, which was maintained for 10 months using only the DNA methyltransferase inhibitor, azacitidine, the patient successfully received the second HSCT. This report describes the clinical effectiveness of azacitidine for the treatment of infant MLL‐r ALL.
DOI:
10.1002/pbc.26697
