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Association details:
| Biomarker: | KLF8 overexpression |
|---|---|
| Cancer: | Triple Negative Breast Cancer |
| Drug: | paclitaxel (Tubulin inhibitor) |
| Direction: | Resistant |
Evidence:
Source:
Title:
3084 - KLF8 is a required downstream effector of OGT/O-GlcNAcylation in regulating breast cancer stem-like cells
Published date:
03/10/2021
Excerpt:
Furthermore, overexpression of KLF8 showed increase in resistance to paclitaxel in triple-negative breast cancer cells in vitro, suggesting a possible role of KLF8 in promoting chemotherapy resistance in breast cancer...