^
    Back
    Association details:
    Biomarker:KLF4 overexpression
    Cancer:Breast Cancer
    Drug:tamoxifen (Estrogen receptor antagonist)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: C3 – Early Trials
    New
    Source:
    Cell Signal
    Title:

    KLF4 overcomes tamoxifen resistance by suppressing MAPK signaling pathway and predicts good prognosis in breast cancer

    Excerpt:
    High KLF4 expression was correlated with enhanced TAM sensitivity in both breast cell lines and breast cancer patients...
    DOI:
    10.1016/j.cellsig.2017.09.025