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Association details:
Biomarker:
KIT fusion
Cancer:
Melanoma
Drug:
Opdivo (nivolumab)
(
PD1 inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: C2 – Inclusion Criteria
Source:
clinicaltrials.gov
Title:
A Phase II Trial of Sunitinib and Nivolumab for KIT-mutated Advanced Melanoma
Excerpt:
A mutation, translocation, or fusion in the KIT gene in the patient's tumor felt to be potentially sensitive to tyrosine kinase inhibition.
Trial ID:
NCT02400385
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