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Association details:
Evidence:
Evidence Level:
Sensitive: C1 - Off-label
  (Approved for Gastrointestinal Stromal Tumor)
New
Excerpt:
Gleevec is a kinase inhibitor indicated for the treatment of...Patients with Kit (CD117) positive unresectable and/or metastatic malignant gastrointestinal stromal tumors (GIST)
Evidence Level:
Sensitive: C4 – Case Studies
New
Title:

A case of c-kit positive high-grade stromal endometrial sarcoma responding to Imatinib Mesylate

Excerpt:
A 41-year-old woman suffering HGES, with positive staining for CD117 (c-kit) and large abdominal and retroperitoneal mass progressing after chemotherapy, was treated with Imatinib Mesylate. After 3 months, objective response was documented and radical surgery performed. Two years after surgical intervention, she is currently free of the disease.
DOI:
10.1016/j.ygyno.2006.01.024