Patients with high expression of HAVCR1 had a significantly better relapse-free survival than low expression (P< 0.001)…However, in subgroup analysis, high HAVCR1 expression was associated with better OS in luminal A (P=0.04)...HAVCR1 is a potential biomarker for breast cancer prognosis. Together, it suggests that HAVCR1 may be a potential therapeutic target in breast cancer.