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    Association details:
    Biomarker:KIF11 overexpression
    Cancer:Triple Negative Breast Cancer
    Drug:docetaxel (Tubulin polymerization promoter, Microtubule stabilizer)
    Direction:Resistant
    Evidence:
    Evidence Level:
    Resistant: C3 – Early Trials
    Source:
    Oncotarget
    Title:

    KIF11 is required for proliferation and self-renewal of docetaxel resistant triple negative breast cancer cells

    Published date:
    11/03/2017
    Excerpt:
    We next analyzed the expression of KIF11 in the docetaxel resistant TNBC cell lines and their paternal cell lines in order to investigate whether KIF11 was involved in TNBC docetaxel resistance.According to the qRT-PCR analysis results, KIF11 mRNA level was significantly increased in both HCC38R and MDA-MB-231R cells (P<0.05...)
    DOI:
    10.18632/oncotarget.20785