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Association details:
Biomarker:KHDRBS3 overexpression
Cancer:Ovarian Cancer
Drug:paclitaxel (Tubulin inhibitor)
Direction:Resistant
Evidence:
Evidence Level:
Resistant: D – Preclinical
Source:
Title:

KHDRBS3 promotes paclitaxel resistance and induces glycolysis through modulated MIR17HG/CLDN6 signaling in epithelial ovarian cancer

Published date:
01/17/2022
Excerpt:
Here, we investigate the role of KHDRBS3 in glycolysis and increased resistance to PTX. The expression of KHDRBS3 was up-regulated in PTX-resistant cells.
DOI:
10.1016/j.lfs.2022.120328