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Association details:
| Biomarker: | KCNQ1OT1 overexpression |
|---|---|
| Cancer: | Hepatocellular Cancer |
| Drug: | sorafenib (Multi-tyrosine kinase inhibitor, pan-RAF inhibitor) |
| Direction: | Resistant |
Evidence:
Source:
Title:
KCNQ1OT1 contributes to sorafenib resistance and programmed death-ligand-1-mediated immune escape via sponging miR-506 in hepatocellular carcinoma cells
Published date:
08/25/2020
Excerpt:
KCNQ1OT1 and PD‑L1 were found to be upregulated and miR‑506 was downregulated in sorafenib‑resistant HCC tissues and cells.
DOI:
10.3892/ijmm.2020.4710