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Association details:
Biomarker:
JARID2 overexpression
Cancer:
Glioma
Drug:
temozolomide
(
DNA synthesis inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Source:
Cancer Biol Ther
Title:
The function and mechanism of the JARID2/CCND1 axis in modulating glioma cell growth and sensitivity to temozolomide (TMZ)
Published date:
07/12/2021
Excerpt:
JARID2 overexpression significantly inhibited glioma cell viability, promoted glioma cell apoptosis upon TMZ treatment.
DOI:
10.1080/15384047.2021.1942711
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