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Association details:
Biomarker:
ITGA4 negative
Cancer:
Chronic Lymphocytic Leukemia
Drug:
lenalidomide
(
TNFα inhibitor
,
IL-6 inhibitor
,
IL-12 inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Source:
Hematol Oncol
Title:
Lenalidomide abrogates the survival effect of bone marrow stromal cells in chronic lymphocytic leukemia
Published date:
05/20/2021
Excerpt:
CD49d-negative CLL cases were more sensitive to lenalidomide treatment.
DOI:
10.1002/hon.2888
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