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    Association details:
    Biomarker:ISX S28G
    Cancer:Colorectal Cancer
    Drug:Erbitux (cetuximab) (EGFR inhibitor)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: C3 – Early Trials
    New
    Source:
    Clin Cancer Res
    Title:

    Novel Chemosensitive Single-Nucleotide Polymorphism Markers to Targeted Regimens in Metastatic Colorectal Cancer

    Excerpt:
    In patients who received cetuximab regimens, patients carrying the homozygous reference alleles of ISX rs361863 (CC) seem to exhibit longer PFS periods…
    DOI:
    10.1158/1078-0432.CCR-10-1907